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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX3X
All Species:
26.06
Human Site:
Y643
Identified Species:
40.95
UniProt:
O00571
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00571
NP_001347.3
662
73243
Y643
G
G
G
Y
G
G
F
Y
N
S
D
G
Y
G
G
Chimpanzee
Pan troglodytes
Q6GVM6
660
73172
Y641
G
G
G
Y
G
G
F
Y
N
S
D
G
Y
G
G
Rhesus Macaque
Macaca mulatta
XP_001095294
910
100218
I892
G
G
G
S
I
E
V
I
C
Y
G
A
I
S
I
Dog
Lupus familis
XP_861268
662
73195
Y643
G
G
G
Y
G
G
F
Y
N
S
D
G
Y
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q62167
662
73083
Y643
G
G
G
Y
G
G
F
Y
N
S
D
G
Y
G
G
Rat
Rattus norvegicus
NP_001102328
659
72976
Y640
G
G
S
Y
G
G
F
Y
N
S
D
G
Y
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512924
651
71975
G629
G
F
G
G
G
G
Y
G
G
F
Y
N
S
D
G
Chicken
Gallus gallus
NP_001025971
651
72031
Y632
G
G
G
Y
G
G
F
Y
N
S
D
G
Y
G
G
Frog
Xenopus laevis
P24346
697
77284
N678
G
G
Y
G
G
F
Y
N
S
D
G
Y
G
G
N
Zebra Danio
Brachydanio rerio
NP_571016
688
75828
N669
G
G
K
G
G
F
G
N
F
Y
S
S
D
G
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VHP0
798
85063
S762
G
N
S
Y
G
G
N
S
G
G
G
G
Y
Y
G
Honey Bee
Apis mellifera
XP_391829
701
78642
S683
G
G
N
Y
N
N
S
S
Y
N
N
S
A
N
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M2F9
646
69224
N607
V
P
G
G
G
Y
G
N
V
P
G
G
G
Y
A
Baker's Yeast
Sacchar. cerevisiae
P24784
617
67899
G599
N
W
G
S
I
G
G
G
F
R
N
D
N
E
K
Red Bread Mold
Neurospora crassa
Q9P6U9
688
72037
G655
G
P
P
A
G
G
Y
G
G
G
G
G
A
G
Y
Conservation
Percent
Protein Identity:
100
91.3
70.1
99.8
N.A.
98.6
95.3
N.A.
95.9
91.2
82.2
76.3
N.A.
51.7
58
N.A.
N.A.
Protein Similarity:
100
95.3
70.3
99.8
N.A.
99
97.1
N.A.
97.2
94.7
88
83.8
N.A.
63.4
70
N.A.
N.A.
P-Site Identity:
100
100
20
100
N.A.
100
93.3
N.A.
33.3
100
26.6
26.6
N.A.
46.6
20
N.A.
N.A.
P-Site Similarity:
100
100
20
100
N.A.
100
93.3
N.A.
40
100
40
26.6
N.A.
46.6
33.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
49.5
49.4
52
Protein Similarity:
N.A.
N.A.
N.A.
64.6
65.2
64.8
P-Site Identity:
N.A.
N.A.
N.A.
20
13.3
33.3
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
0
0
0
0
0
0
7
14
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
7
40
7
7
7
0
% D
% Glu:
0
0
0
0
0
7
0
0
0
0
0
0
0
7
0
% E
% Phe:
0
7
0
0
0
14
40
0
14
7
0
0
0
0
0
% F
% Gly:
87
67
60
27
80
67
20
20
20
14
34
60
14
60
54
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
14
0
0
7
0
0
0
0
7
0
7
% I
% Lys:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
7
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
7
7
0
7
7
7
20
40
7
14
7
7
7
14
% N
% Pro:
0
14
7
0
0
0
0
0
0
7
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% R
% Ser:
0
0
14
14
0
0
7
14
7
40
7
14
7
7
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
7
0
0
0
0
0
7
0
7
0
0
0
0
0
0
% V
% Trp:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
54
0
7
20
40
7
14
7
7
47
14
14
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _